The popularity of GLP-1 receptor agonists such as semaglutide — Ozempic and Wegovy — and tirzepatide — Mounjaro and Zepbound — has skyrocketed in the last couple of years, with many patients seeking these medications as a quick solution for weight loss. This category of medication was originally developed to manage type 2 diabetes because these drugs mimic the effects of the GLP-1 hormone, which regulates blood sugar, slows gastric emptying and reduces appetite. Clinical studies showed significant weight loss. As a practitioner, I urge patients and the public to approach these medications thoughtfully and prioritize long-term health over rapid weight loss results.

 

One of the most critical aspects of safe weight loss is pacing. Slow and steady wins the race. Losing weight too quickly — often seen when patients rely solely on GLP-1 medications without addressing lifestyle factors — can lead to muscle loss, gallstones, nutrient deficiencies and metabolic slowdown. The goal with weight loss should always be sustainable fat loss, not necessarily just a lower number on the scale.

 

At Body Balance, we follow the Centers for Disease Control’s recommendation for weight loss of around 1-2 pounds per week. During the weight-loss phase, I also use the technology of a bioelectrical impedance scale to measure my patients’ water weight, amount of muscle, pounds of fat, visceral fat and even the minimum number of calories they should be eating each day. By breaking up all of these numbers, we can truly see why the weight is measuring as it is on the scale.  

 

GLP-1 medications can be life-changing when used appropriately, particularly for those with obesity-related health conditions. However, they work best as part of a comprehensive plan that includes dietary changes, physical activity and behavioral support. Patients should understand that these drugs are not a magic shot; they require commitment and monitoring by a health care provider to ensure efficacy and safety.

 

When patients reach their goal weight, many don’t realize that discontinuing GLP-1 medications abruptly often leads to weight regain if underlying habits aren’t addressed. This highlights the importance of coupling medication use with long-term lifestyle interventions.

 

The excitement around GLP-1’s class of medications is understandable; they represent a breakthrough in obesity treatment. As a practitioner, I want to remind patients that lasting health is built over time. A balanced approach to weight loss, prioritizing gradual progress and sustainable habits should remain the focus of your weight loss efforts.